Semaglutide is a medication used in the treatment of type 2 diabetes and obesity. It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. These medications work by mimicking the action of a hormone called GLP-1, which helps regulate blood sugar levels and promotes feelings of fullness after eating, leading to weight loss.
Semaglutide is typically administered as an injection under the skin once a week. It helps lower blood sugar levels by stimulating insulin release, slowing down stomach emptying, and reducing the production of glucagon (a hormone that raises blood sugar levels).
In addition to its use in diabetes management, semaglutide has also been approved by the FDA for the treatment of obesity in adults with a BMI (body mass index) of 30 or higher, or with a BMI of 27 or higher and at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol).
It's important to note that semaglutide, like any medication, may have side effects and should be used under the guidance of a healthcare professional. Common side effects may include nausea, vomiting, diarrhea, and abdominal pain.
| Product Name | Semaglutide Peptide |
|---|---|
| Storage Conditions | Store At 2-25°C |
| Test Method | HPLC UV |
| Form | 99% Raw Powder |
| COA | Available |
| Indication | Weight Loss |
| Shelf Life | 2 Years |
| CAS | 910463-68-2 |
| Active Ingredient | Semaglutide |
| Shipping Method | Air(UPS, FedEx, TNT, EMS) Or Sea |
The function of semaglutide revolves around its role as a glucagon-like peptide-1 (GLP-1) receptor agonist. Here's a breakdown of how semaglutide works and its key functions:
1. GLP-1 Receptor Activation: Semaglutide binds to and activates GLP-1 receptors, which are found on various cells throughout the body, including pancreatic beta cells, gastrointestinal cells, and neurons in the brain.
2. Insulin Release: One of the primary functions of semaglutide is to stimulate the secretion of insulin from pancreatic beta cells in response to elevated blood glucose levels. This helps lower blood sugar levels after meals, promoting better glycemic control in individuals with type 2 diabetes.
3. Glucagon Suppression: Semaglutide also reduces the secretion of glucagon, a hormone that raises blood sugar levels. By inhibiting glucagon release, semaglutide helps prevent excessive glucose production by the liver, contributing to overall blood sugar regulation.
4. Slowing Gastric Emptying: Another important function of semaglutide is its ability to slow down the emptying of food from the stomach into the small intestine. This delayed gastric emptying leads to a slower and more gradual rise in blood glucose levels after meals, helping to prevent postprandial hyperglycemia (high blood sugar levels after eating).
5. Appetite Regulation: Semaglutide can also impact appetite and satiety. By activating GLP-1 receptors in the brain's appetite control centers, it promotes feelings of fullness and reduces food intake, which can be beneficial for weight management in individuals with obesity.
6. Weight Loss: The combination of reduced appetite, slower gastric emptying, and improved glycemic control often leads to weight loss in individuals taking semaglutide. This weight loss effect is particularly notable in higher doses used specifically for obesity treatment.
7. Cardiovascular and Renal Benefits: Beyond its effects on blood sugar and weight, semaglutide has demonstrated additional benefits such as improvements in cardiovascular risk factors (e.g., blood pressure, cholesterol levels) and potential renal protective effects in certain patient populations.
Overall, the function of semaglutide is multifaceted, encompassing improvements in blood sugar control, appetite regulation, weight management, and potential cardiovascular and renal benefits. Its mechanism of action as a GLP-1 receptor agonist makes it a valuable medication for the treatment of type 2 diabetes, obesity, and related metabolic conditions.
