Hypoglycemic Drugs 99% Raw Glibenclamide Powder CAS 10238-21-8
Product Description
1) Product name: Medicine Grade Glibenclamide/Glibenclamide
2) CAS No.: 10238-21-8
3) Molecular Weight: 487.9559
4) Appearance: White powder
5) Molecular Formula: C23H22ClN3O5S
6) Specification: 99%
7) Testing Method: HPLC
Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker.
Function and Application
1. Hypoglycemic drugs, for the treatment of mild, non-insulin-dependent diabetes mellitus.
2. Glibenclamide and glibenclamide, glibenclamide, which belongs to the second generation oral sulfonylurea drugs, with the mechanism of toluene sulfonyl Ding Niao, its hypoglycemic effect was the strongest sulfonylurea, intensity for tolbutamide 200 ~ 250 times. Be selective effect on pancreatic beta cells, promote the secretion of insulin, and can enhance the hypoglycemic effect of exogenous insulin, and insulin receptor after strengthening effect.
3. Glibenclamide is one of the drugs currently used to treat type 2 diabetes, it the most often used because the utility function is fast and strong, so after the application has obvious effect, can effectively control blood sugar, high blood sugar, is applicable to other sulfonylureas hypoglycemic effect not beautiful person.
