Chlorpheniramine Maleate CAS 113-92-8 Antihistaminic
Product Description
Product name | chlorpheniramine maleate |
Appearance | White Powder |
CAS | 113-92-8 |
MF | C20H23ClN2O4 |
Purity | 99% |
Shelf life | 2 years |
Storage | Keep in cool dry place. |
Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
Function
Chlorpheniramine maleate is an antihistamine medication used as an activeingredient in many different non-prescription medicines and prescription drugs.
This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
By blocking another natural substance made by your body (acetylcholine), it helps dry up some body fluids to relieve symptoms such as watery eyesand runny nose.
Application
Chloropheniramine maleate is one of the most commonly used antihistamines in small-animal veterinary practice as well.
Although not generally approved as an antidepressant or anti-anxiety medication, chlorpheniramine appears to have these properties as well.