| Product Name | GS-441524 |
| Expiry Date | 1 Year From The Date Of Manufacture |
| Storage Condition | Room Temperature |
| CAS | 1191237-69-0 |
| Function | Treatment For Cat FIP |
| Dosage Form | Injection |
| Country of Manufacture | China |
| Packaging | 6ml/vial, 8ml/vial, 10ml/vial |
| Strength | 20mg and 30mg |
GS-441524 injection solution is an antiviral treatment used for Feline Infectious Peritonitis (FIP), a lethal disease in cats caused by a feline coronavirus mutation. GS-441524, a nucleoside analog, inhibits the virus's replication, reducing viral load and allowing the cat's immune system to combat the infection. Administered via subcutaneous injections, this treatment has shown high efficacy in clinical studies and real-world applications, leading to significant recovery rates, even in severe cases. Despite its lack of official approval in many countries, GS-441524 has become a critical option for veterinarians and cat owners seeking to treat FIP. The injectable form is especially beneficial for cats with gastrointestinal issues or those who struggle with oral medications.
There are two main forms of FIP: effusive (wet) and non-effusive (dry). The wet form is characterized by the accumulation of fluid in the abdomen or chest, leading to symptoms like distended abdomen, difficulty breathing, and lethargy. The dry form does not involve fluid accumulation but causes inflammatory lesions in organs such as the liver, kidneys, spleen, and central nervous system. Cats with the dry form may exhibit neurological symptoms, jaundice, or ocular changes.
The symptoms of FIP can vary widely depending on the form and the organs affected. Common signs include:
Fever: Persistent fever that does not respond to antibiotics.
Weight Loss: Cats may lose weight despite having a normal or reduced appetite.
Lethargy: Affected cats often become lethargic and less active.
Abdominal Swelling: Particularly in the wet form, fluid buildup can cause noticeable swelling.
Respiratory Distress: Difficulty breathing due to fluid in the chest.
Neurological Signs: Such as seizures, tremors, or altered mental status, especially in the dry form.
GS-441524 is an antiviral drug that has shown promise in the treatment of feline infectious peritonitis (FIP), a viral disease caused by certain strains of feline coronavirus. As of my last update, GS-441524 is primarily used off-label in cats with FIP.
The dosage of GS-441524 injection for cats with FIP can vary depending on factors such as the cat's weight, the severity of the disease, and the veterinarian's assessment. Dosage regimens may also vary based on individual response and the specific formulation of GS-441524 being used.
Recommended dosage:
FIP(Wet): 0.3ml/kg * body weight kg + 0.1ml residue
FIP (Dry): 0.4ml/kg * body weight kg + 0.1ml residue
Eye / nerve entry: 0.5ml/kg * body weight kg + 0.1ml residue
Recurrence: 0.6 ml / kg * body weight kg + 0.1ml residue
