| Product Name | GS-441524 |
| Expiry Date | 1 Year From The Date Of Manufacture |
| Storage Condition | Room Temperature |
| CAS | 1191237-69-0 |
| Function | Treatment For Cat FIP |
| Dosage Form | Injection |
| Country of Manufacture | China |
| Packaging | 6ml/vial, 8ml/vial, 10ml/vial |
| Strength | 20% |
The 20% GS-441524 Ampoule is a potent antiviral solution primarily used in veterinary medicine for the treatment of feline infectious peritonitis (FIP) caused by feline coronavirus. Each ampoule contains a 20% concentration of GS-441524, a nucleoside analog that inhibits viral replication by targeting the RNA-dependent RNA polymerase enzyme. This product is known for its high efficacy in treating various forms of FIP, including effusive, non-effusive, and ocular/neurological manifestations.
The 20% concentration ensures a higher dose in a smaller volume, making administration more convenient and efficient. The ampoule is designed for subcutaneous injection and should be administered under the guidance of a veterinarian. The solution is sterile, free of preservatives, and formulated to be stable and easy to store. The 20% GS-441524 Ampoule is a critical tool in the management of FIP, offering hope to pet owners and veterinarians dealing with this challenging disease.
Feline Infectious Peritonitis (FIP) is a severe, often fatal, viral disease affecting cats. It is caused by a mutation of the feline coronavirus (FCoV). While many cats are exposed to the feline coronavirus, only a small percentage develop FIP. The disease primarily affects young cats, though it can occur at any age.
Forms of FIP:
FIP manifests in two primary forms: effusive (wet) and non-effusive (dry).
1. Effusive FIP: This form is characterized by the accumulation of fluid in the abdomen or chest, leading to swelling and difficulty breathing. It progresses rapidly and is often easier to diagnose due to the presence of the fluid.
2. Non-Effusive FIP: The dry form does not involve fluid buildup but instead causes lesions on internal organs like the liver, kidneys, or eyes. This form progresses more slowly and can be harder to diagnose, as its symptoms vary widely depending on the affected organs.
GS-441524 is an antiviral drug that has shown promise in the treatment of feline infectious peritonitis (FIP), a viral disease caused by certain strains of feline coronavirus. As of my last update, GS-441524 is primarily used off-label in cats with FIP.
The dosage of GS-441524 injection for cats with FIP can vary depending on factors such as the cat's weight, the severity of the disease, and the veterinarian's assessment. Dosage regimens may also vary based on individual response and the specific formulation of GS-441524 being used.
Recommended dosage:
FIP(Wet): 0.3ml/kg * body weight kg + 0.1ml residue
FIP (Dry): 0.4ml/kg * body weight kg + 0.1ml residue
Eye / nerve entry: 0.5ml/kg * body weight kg + 0.1ml residue
Recurrence: 0.6 ml / kg * body weight kg + 0.1ml residue
