| Product Name | GS-441524 |
| Expiry Date | 1 Year From The Date Of Manufacture |
| Storage Condition | Room Temperature |
| CAS | 1191237-69-0 |
| Function | Treatment For Cat FIP |
| Dosage Form | Injection |
| Country of Manufacture | China |
| Packaging | 6ml/vial, 8ml/vial, 10ml/vial |
| Strength | 30% |
The 30% GS-441524 Vials are a highly concentrated antiviral solution specifically designed for the treatment of feline infectious peritonitis (FIP) in cats. Each vial contains a 30% concentration of GS-441524, an effective nucleoside analog that disrupts the replication of the feline coronavirus by inhibiting the RNA-dependent RNA polymerase enzyme. This higher concentration allows for the delivery of a potent dose in a smaller volume, enhancing the ease of administration while reducing the number of injections required for effective treatment.
The 30% GS-441524 solution is intended for subcutaneous injection and is typically used in cases where a more aggressive treatment regimen is needed, such as in severe or resistant forms of FIP, including those affecting the neurological system. The vials are sterile, preservative-free, and carefully formulated to ensure stability, making them convenient for storage and handling. Administering this product should be done under the supervision of a qualified veterinarian to ensure proper dosing and monitoring. The 30% GS-441524 Vials represent a significant advancement in FIP treatment, providing an essential option for veterinarians and cat owners facing this devastating disease.
Feline Infectious Peritonitis (FIP) is a severe, often fatal, viral disease affecting cats. It is caused by a mutation of the feline coronavirus (FCoV). While many cats are exposed to the feline coronavirus, only a small percentage develop FIP. The disease primarily affects young cats, though it can occur at any age.
Forms of FIP:
FIP manifests in two primary forms: effusive (wet) and non-effusive (dry).
1. Effusive FIP: This form is characterized by the accumulation of fluid in the abdomen or chest, leading to swelling and difficulty breathing. It progresses rapidly and is often easier to diagnose due to the presence of the fluid.
2. Non-Effusive FIP: The dry form does not involve fluid buildup but instead causes lesions on internal organs like the liver, kidneys, or eyes. This form progresses more slowly and can be harder to diagnose, as its symptoms vary widely depending on the affected organs.
GS-441524 is an antiviral drug that has shown promise in the treatment of feline infectious peritonitis (FIP), a viral disease caused by certain strains of feline coronavirus. As of my last update, GS-441524 is primarily used off-label in cats with FIP.
The dosage of GS-441524 injection for cats with FIP can vary depending on factors such as the cat's weight, the severity of the disease, and the veterinarian's assessment. Dosage regimens may also vary based on individual response and the specific formulation of GS-441524 being used.
Recommended dosage:
FIP(Wet): 0.3ml/kg * body weight kg + 0.1ml residue
FIP (Dry): 0.4ml/kg * body weight kg + 0.1ml residue
Eye / nerve entry: 0.5ml/kg * body weight kg + 0.1ml residue
Recurrence: 0.6 ml / kg * body weight kg + 0.1ml residue
