| Product Name | GS-441524 |
| Expiry Date | 1 Year From The Date Of Manufacture |
| Storage Condition | Room Temperature |
| CAS | 1191237-69-0 |
| Function | Treatment For Cat FIP |
| Dosage Form | Injection |
| Country of Manufacture | China |
| Packaging | 6ml/vial, 8ml/vial, 10ml/vial |
| Strength | 20mg and 30mg |
GS-441524 Injectable is an experimental antiviral treatment that has gained attention, particularly in veterinary circles. It is a nucleotide analog and a precursor to remdesivir, an antiviral drug used to combat COVID-19 in humans. GS-441524 became well-known for its success in treating feline infectious peritonitis (FIP), a lethal viral condition in cats caused by a type of coronavirus.
This drug has shown exceptional promise in managing FIP, a disease that was previously untreatable in cats, by blocking the virus from replicating within the body.
Administered as an injection under the skin, GS-441524 has delivered impressive results, showing a high success rate in curing FIP in cats.
Feline Infectious Peritonitis (FIP) is a fatal disease caused by a feline coronavirus, primarily affecting young cats or those with weakened immune systems. Most cats infected with the common feline coronavirus show mild digestive symptoms or remain asymptomatic. However, in some cases, the virus mutates within the cat's body, leading to the development of FIP. There are two main forms of FIP: wet and dry. Wet FIP is characterized by fluid accumulation in the abdomen or chest, causing swelling and difficulty breathing, while dry FIP does not involve fluid buildup but causes inflammation in organs, often accompanied by neurological symptoms like seizures or abnormal behavior.
Symptoms of FIP vary and may include fever, loss of appetite, weight loss, lethargy, and other non-specific signs, making diagnosis challenging. Blood tests, ultrasounds, and fluid analysis from the abdomen are commonly used to aid in diagnosis. Historically, FIP was considered untreatable, and care was mainly palliative to improve the cat’s quality of life.
In recent years, experimental antiviral drugs like GS-441524 have shown great potential in treating FIP. By inhibiting the virus from replicating, this treatment has helped many cats recover fully. While not yet widely approved, this breakthrough has given hope to many cat owners. Prevention includes maintaining a clean, low-stress environment to reduce the risk of feline coronavirus infection.
GS-441524 is an antiviral drug that has shown promise in the treatment of feline infectious peritonitis (FIP), a viral disease caused by certain strains of feline coronavirus. As of my last update, GS-441524 is primarily used off-label in cats with FIP.
The dosage of GS-441524 injection for cats with FIP can vary depending on factors such as the cat's weight, the severity of the disease, and the veterinarian's assessment. Dosage regimens may also vary based on individual response and the specific formulation of GS-441524 being used.
Recommended dosage:
FIP(Wet): 0.3ml/kg * body weight kg + 0.1ml residue
FIP (Dry): 0.4ml/kg * body weight kg + 0.1ml residue
Eye / nerve entry: 0.5ml/kg * body weight kg + 0.1ml residue
Recurrence: 0.6 ml / kg * body weight kg + 0.1ml residue
