Product Name | GS-441524 |
Expiry Date | 1 Year From The Date Of Manufacture |
Storage Condition | Room Temperature |
CAS | 1191237-69-0 |
Function | Treatment For Cat FIP |
Dosage Form | Injection |
Country of Manufacture | China |
Packaging | 6ml/vial, 8ml/vial, 10ml/vial |
Strength | 20mg and 30mg |
GS-441524 Injectable is an experimental antiviral medication that has drawn significant interest, particularly among veterinary professionals. It is a nucleotide analog and serves as a precursor to remdesivir, the antiviral drug that has been used to treat COVID-19 in humans. GS-441524 rose to prominence due to its effectiveness in treating feline infectious peritonitis (FIP), a deadly viral disease caused by a type of coronavirus in cats.
This drug has shown considerable promise in treating FIP, a condition once thought to be incurable in cats. It works by stopping the virus responsible for FIP from multiplying.
GS-441524 is administered via injection under the skin (subcutaneously) to cats diagnosed with FIP, and has achieved a high rate of success in treating the disease.
Feline Infectious Peritonitis (FIP) is a serious and often fatal disease in cats, caused by a mutation of the feline coronavirus. While most cats contract the benign form of the virus, which typically causes mild intestinal issues or no symptoms at all, a small percentage experience a mutation that leads to FIP. This disease primarily affects young or immunocompromised cats and comes in two forms: wet and dry. Wet FIP is marked by fluid buildup in the abdomen or chest, leading to bloating and breathing difficulties, while dry FIP presents with organ inflammation, often impacting the nervous system, causing symptoms like seizures or behavioral changes.
Diagnosing FIP can be difficult due to its vague symptoms, such as fever, lethargy, loss of appetite, and weight loss. Blood tests, imaging, and fluid analysis are often used to help make a diagnosis. Until recently, FIP was considered incurable, with treatment focused on symptom management. However, experimental antiviral drugs like GS-441524 have shown a high success rate in treating the disease, giving new hope to cats suffering from FIP. While not yet approved globally, this treatment has proven life-saving for many. Preventing FIP involves reducing stress and maintaining cleanliness to minimize the risk of feline coronavirus mutation.
GS-441524 is an antiviral drug that has shown promise in the treatment of feline infectious peritonitis (FIP), a viral disease caused by certain strains of feline coronavirus. As of my last update, GS-441524 is primarily used off-label in cats with FIP.
The dosage of GS-441524 injection for cats with FIP can vary depending on factors such as the cat's weight, the severity of the disease, and the veterinarian's assessment. Dosage regimens may also vary based on individual response and the specific formulation of GS-441524 being used.
Recommended dosage:
FIP(Wet): 0.3ml/kg * body weight kg + 0.1ml residue
FIP (Dry): 0.4ml/kg * body weight kg + 0.1ml residue
Eye / nerve entry: 0.5ml/kg * body weight kg + 0.1ml residue
Recurrence: 0.6 ml / kg * body weight kg + 0.1ml residue