| Product Name | GS-441524 |
| Expiry Date | 1 Year From The Date Of Manufacture |
| Storage Condition | Room Temperature |
| CAS | 1191237-69-0 |
| Function | Treatment For Cat FIP |
| Dosage Form | Injection |
| Country of Manufacture | China |
| Packaging | 6ml/vial, 8ml/vial, 10ml/vial |
| Strength | 20mg and 30mg |
GS-441524 Injectable is an investigational antiviral drug that has attracted widespread interest, particularly among veterinary professionals. It’s a nucleotide analog that serves as a precursor to remdesivir, the antiviral medication used in treating COVID-19. GS-441524 gained recognition for its effectiveness in addressing feline infectious peritonitis (FIP), a deadly viral disease caused by a coronavirus in cats.
The drug has shown remarkable promise in treating FIP, which was once deemed untreatable in cats, by inhibiting the virus's ability to reproduce.
Administered via injection under the skin (subcutaneously), GS-441524 has achieved a high rate of success in curing cats suffering from FIP.
"FIP" refers to Feline Infectious Peritonitis (FIP), which is a viral disease caused by certain strains of feline coronavirus (FCoV).
FIP is caused by a mutation of the feline coronavirus (FCoV). Most cats with FCoV do not develop FIP, but in some cases, the virus mutates into a form that causes FIP.
FCoV is commonly spread through feces and oral-fecal transmission, often in multi-cat environments such as shelters or catteries. Once a cat is infected with FCoV, it may develop either a mild, self-limiting form of the disease or progress to FIP.
FIP presents in two main forms: effusive (wet) and non-effusive (dry). Effusive FIP involves the accumulation of fluid in body cavities, such as the abdomen or chest. Non-effusive FIP is characterized by granulomatous lesions in various organs.
Symptoms of FIP can vary widely and may include fever, weight loss, lethargy, jaundice, difficulty breathing, and fluid accumulation in the abdomen or chest in the case of effusive FIP. Neurological symptoms can also occur in some cases.
GS-441524 is an antiviral drug that has shown promise in the treatment of feline infectious peritonitis (FIP), a viral disease caused by certain strains of feline coronavirus. As of my last update, GS-441524 is primarily used off-label in cats with FIP.
The dosage of GS-441524 injection for cats with FIP can vary depending on factors such as the cat's weight, the severity of the disease, and the veterinarian's assessment. Dosage regimens may also vary based on individual response and the specific formulation of GS-441524 being used.
Recommended dosage:
FIP(Wet): 0.3ml/kg * body weight kg + 0.1ml residue
FIP (Dry): 0.4ml/kg * body weight kg + 0.1ml residue
Eye / nerve entry: 0.5ml/kg * body weight kg + 0.1ml residue
Recurrence: 0.6 ml / kg * body weight kg + 0.1ml residue
