40mg GS-441524 Tablets HPLC 99% Single-Press Uniform Dose Moisture-Sealed|
Product Overview
The 40mg tablet sits in the middle of the range, and it is the strength most study designs settle on once the dose ladder has been narrowed. Each tablet comes off a dedicated press line, from a blended mass that is checked before compression rather than after, so the active content is fixed going into the run instead of being corrected afterwards. Purity is measured at 99% by HPLC on every lot, and the molecular weight is confirmed at 291.26 against the reference standard, so what sits inside the tablet matches the structure a protocol calls for.
GS-441524 is a nucleoside analogue. Its action is on the viral RNA-dependent RNA polymerase: the molecule enters the copying strand and blocks further extension, which is where the antiviral effect begins.
Key Features & Advantages
Assay on record: the chromatogram and MS data for the lot travel with the shipment, so the purity figure can be traced to a report rather than read off a label.
Weight hold: tablets from the same run are pulled at intervals and weighed. That sampling, more than the press setting, is what keeps 40mg at 40mg across a batch.
Blended before pressing: pre-blending spreads the active material through the whole mass, avoiding the uneven pockets that hand-filled capsules are known for.
Impurity control: a multi-stage filtration and drying sequence removes residual solvents and heavy metals, a detail that starts to matter once an observation period runs past twelve weeks.
Sealed against humidity: foil-lined packing holds the tablets within spec through warm, humid freight lanes and storage that is not climate controlled.
Application Scenarios
Feline coronavirus research: a fixed-strength oral material for RNA polymerase inhibition work.
Dose-response studies: the 40mg unit takes the weighing step out of repeated oral schedules.
Pharmacokinetics: even tablets make absorption and half-life comparisons across breeds readable.
Method development: a sample of known concentration for labs building their own assay.
Supply & Delivery
Orders leave in plain, unbranded packaging with the documents sealed inside. Customs paperwork is prepared for destinations with tight import rules, and larger volumes can be divided across several consignments so nothing sits in one place for long.![]()