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Pharmaceutical Grade GS 441524 FIP Cat GS-441 Injection Liquid

10 vials
MOQ
Negotiable
Price
Pharmaceutical Grade GS 441524 FIP Cat  GS-441 Injection Liquid
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Features
Specifications
Grade: Pharmaceutcial Grade
Function: Cat FIPV
CAS: 1191237-69-0
Purity: 20mg/mL
Shelf Life: 2 Years
Test Method: HPLC UV
Storage: Cool Dry Place
Sample: Available
Shipping Method: Air(UPS, FedEx, TNT, EMS) Or Sea
MF: C12H13N5O4
High Light:

Pharmaceutical Grade Gs 44152 Fip

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Gs 44152 Fip Cat

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Cat GS-441 Injection

Basic Infomation
Model Number: GS-441524
Payment & Shipping Terms
Packaging Details: 10 vials/ box
Delivery Time: 2-3 days
Payment Terms: D/A, D/P, L/C, T/T, Western Union, MoneyGram
Supply Ability: 100000 vials per month
Product Description

 

GS-441 Supplier Cat FIP Injection With Fast Delivery

 

Product Description

 

This medicine is an adenosine nucleotide analog antiviral, similar to remdesivi.This molecule was patented in 2009. In vitro studies of GS have determined it has a higher EC50 than remdesivi against a number of viruses, meaning GS is less potent.This medicine continues to be studied in the treatment of Feline Infectious Peritonitis Virus, that only infects cats.

 

Appearance

Transparent liquid, powder or tablets

GS Standard

99.5%min

Size

5.5 ml/ Vial

Content

15mg/ml or 20mg/ml

Application

For CAT FIP R&D Use ONLY

Wet FIP

6-7 mg/kg

Dry FIP

7-8 mg/kg

Ocular or Neuro FIP

8 mg/kg

Increased ocular/neuro

9 mg/kg

Max ocular/neuro

10 mg/kg

 

 

How GS441524 Cures FIP?
 
If a cat's immune system is healthy and mature, the white blood cells should fight off an infection or virus, and allow the cat to build up an immune response, or antibodies. Cats who develop FIP have an immune defect or deficiency that causes the white blood cells to replicate, rather than fight, the virus. Essentially, the cats immune system is spreading the virus throughout the cat's body rather than trying to eliminate it. Cats who have no immune response develop wet FIP, while cats who have a partial immune response develop dry FIP.
 
The nucleoside analog GS is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. In layman's terms, GS interjects itself into the chain reaction and stops the replication of the virus.

 

FAQ

 

Q: What is GS441?

A: GS is short for GS which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field .
It is currently available as an injection or an oral medication although the oral version is still not widely available yet. Please checking with Julia for the details!

Q: How long is the treatment?
A: Recommended treatment based on Niche Petcare is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat's symptoms should be assessed to see if additional treatment is needed.

Q: What is the correct dose of GS441 to give my kitty?
A: Dosing is based on the weight of the cat.
If you love math, the formula to calculate is:
5mg*(GS) x weight(kg) / GS concentration per 1mL**=dose per 24hr
*Neurological and Ocular FIP cats require 8mg/kg MINIMUM.
Can go as high as 10mg/kg for extreme ocular or neurological cases.
*GS concentration per 1ml = total GS in bottle (mg) / total solution volume (mL)

Q: What exactly are "neuro" or "ocular" cases?
A: "Neuro" cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected

Q: How do I give the GS441 injections?

A: The injections are given sub-cutaneously or "sub-cu" which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It's best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet.

Q: What are the side effects of GS441?
A: The only known side effects of GS are pain during injections and the possibility of skin lesions forming at the injection sites.

Q: My kitty is on GS and now has diarrhea. What should I do?
A: We recommend giving B-12, bland food and a probiotic. Pumpkin puree is also okay to give. Fortiflora or Proviable are two probiotics. If the cat seems to be getting dehydrated, giving sub-cutaneous fluids is okay

Q: Should I continue to use flea/tick treatment for my FIP kitty during treatment?
A: No. Do not use Revolution, Frontline or other chemical flea/tick treatments while on FIP treatment. The biggest part of treating for fleas is the environment. Vacuum daily (floors, closets, bedding, anything the cats come in contact with) and wash all bedding. You can flea comb your cat daily to remove fleas. You can make a mixture of water and apple cider vinegar (2:1) to apply on a cloth and wipe onto your cat daily so the fleas don't want to be on her. Revolution is one of the moresafe options, but I would hesitate to combine it with GS for fear of affecting the GS being able to have full effect.

Q: How long after completing FIP treatment should I wait to spay/neuter my cat?
A: 3 months.

Pharmaceutical Grade GS 441524 FIP Cat  GS-441 Injection Liquid 0

 

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